Melanoma antigen recognition by tumour-infiltrating T lymphocytes (TIL): effect of differential expression of Melan-A/MART-1

We have isolated, from an individual patient with metastatic melanoma, a series of eight TIL clones capable of lysing autologous melanoma cell targets. Six of the eight clones expressed TCRAV2S1 and lysed targets expressing HLA-A2 and the Melan-A/MART-1 peptide: AAGIGILTV. Polymerase chain reaction-...

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Autori principali: Ramirez-Montagut, T, Andrews, D M, Ihara, A, Pervaiz, S, Pandolfi, F, Van Den Elsen, P J, Waitkus, R, Boyle, L A, Hishii, M, Kurnick, J T
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2000
Soggetti:
Cancer Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905547/
https://ncbi.nlm.nih.gov/pubmed/10606959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01089.x
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