Dual Reporter Comparative Indexing of rAAV Pseudotyped Vectors in Chimpanzee Airway

Selecting the most efficient recombinant adeno-associated virus (rAAV) serotype for airway gene therapy has been difficult due to cross-specific differences in tropism and immune response between humans and animal models. Chimpanzees—the closest surviving genetic relative of humans—provide a valuabl...

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Detalhes bibliográficos
Main Authors: Flotte, Terence R, Fischer, Anne C, Goetzmann, Jason, Mueller, Christian, Cebotaru, Liudmila, Yan, Ziying, Wang, Lilli, Wilson, James M, Guggino, William B, Engelhardt, John F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839428/
https://ncbi.nlm.nih.gov/pubmed/19826405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.230
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