Induction of Tumor-specific Immune Response by Gene Transfer of Hsp70-cell-penetrating Peptide Fusion Protein to Tumors in Mice

To induce a tumor-specific immune response by delivering tumor-associated antigens in tumor cells to antigen-presenting cells (APCs), we designed a fusion protein which consists of heat-shock protein 70 (Hsp70) and the C-terminal 34 amino acids of herpes simplex virus VP22 protein (VP22(268–301)), t...

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Detalhes bibliográficos
Main Authors: Nishikawa, Makiya, Otsuki, Takayuki, Ota, Atsushi, Guan, Xin, Takemoto, Seiji, Takahashi, Yuki, Takakura, Yoshinobu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839311/
https://ncbi.nlm.nih.gov/pubmed/19724264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.203
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