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Mechanisms of resistance to anti-EGFR monoclonal antibody treatment in metastatic colorectal cancer

Metastatic colorectal cancer (mCRC) continues to be counted as a major health problem. The introduction of newer cytotoxics, irinotecan and oxaliplatin, has achieved a significant improvement in survival rates. Novel targeted therapies (bevacizumab, and cetuximab) in combination with most efficient...

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Autores principales: Saridaki, Zacharenia, Georgoulias, Vassilis, Souglakos, John
Formato: Artigo
Lenguaje:Inglês
Publicado: The WJG Press and Baishideng 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839169/
https://ncbi.nlm.nih.gov/pubmed/20222160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v16.i10.1177
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