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EGFR gene copy number as a predictive biomarker for resistance to anti-EGFR monoclonal antibodies in metastatic colorectal cancer treatment: a meta-analysis

OBJECTIVE: The epidermal growth factor receptor (EGFR) inhibitors monoclonal antibodies (MoAbs) have already shown the therapeutic effectiveness in patients with metastatic colorectal cancer (mCRC). But many patients resist to the treatment. The aim of this meta-analysis was to assess EGFR gene copy...

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Detalhes bibliográficos
Main Authors: Shen, Wei-Dong, Chen, Hong-Lin, Liu, Peng-Fei
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937753/
https://ncbi.nlm.nih.gov/pubmed/24653627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.1000-9604.2014.01.10
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