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IL-15 trans-presentation by pulmonary dendritic cells promotes effector CD8 T cell survival during influenza virus infection

We have recently demonstrated that peripheral CD8 T cells require two separate activation hits to accumulate to high numbers in the lungs after influenza virus infection: a primary interaction with mature, antigen-bearing dendritic cells (DCs) in the lymph node, and a second, previously unrecognized...

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Detalhes bibliográficos
Main Authors: McGill, Jodi, Van Rooijen, Nico, Legge, Kevin L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839152/
https://ncbi.nlm.nih.gov/pubmed/20212069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091711
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