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Essential roles of sphingosine-1–phosphate receptor 2 in human mast cell activation, anaphylaxis, and pulmonary edema

Systemic exacerbation of allergic responses, in which mast cells play a critical role, results in life-threatening anaphylactic shock. Sphingosine-1–phosphate (S1P), a ligand for a family of G protein–coupled receptors, is a new addition to the repertoire of bioactive lipids secreted by activated ma...

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Bibliografske podrobnosti
Main Authors: Oskeritzian, Carole A., Price, Megan M., Hait, Nitai C., Kapitonov, Dmitri, Falanga, Yves T., Morales, Johanna K., Ryan, John J., Milstien, Sheldon, Spiegel, Sarah
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839150/
https://ncbi.nlm.nih.gov/pubmed/20194630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091513
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