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Experimental Approaches to the Study of Epigenomic Dysregulation in Ageing

In this review, we describe how normal ageing may involve the acquisition of epigenetic errors over time, akin to the accumulation of genetic mutations with ageing. We describe how such experiments are currently performed, their limitations technically and analytically and their application to agein...

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Detalhes bibliográficos
Main Authors: Thompson, Reid F., Fazzari, Melissa J., Greally, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838972/
https://ncbi.nlm.nih.gov/pubmed/20060885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2009.12.013
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