An Integrative Genomic and Epigenomic Approach for the Study of Transcriptional Regulation

The molecular heterogeneity of acute leukemias and other tumors constitutes a major obstacle towards understanding disease pathogenesis and developing new targeted-therapies. Aberrant gene regulation is a hallmark of cancer and plays a central role in determining tumor phenotype. We predicted that i...

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Autori principali: Figueroa, Maria E., Reimers, Mark, Thompson, Reid F., Ye, Kenny, Li, Yushan, Selzer, Rebecca R., Fridriksson, Jakob, Paietta, Elisabeth, Wiernik, Peter, Green, Roland D., Greally, John M., Melnick, Ari
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266992/
https://ncbi.nlm.nih.gov/pubmed/18365023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001882
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