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Upregulation of Elastase Activity in Aorta in Mucopolysaccharidosis I and VII Dogs May be Due to Increased Cytokine Expression
Mucopolysaccharidosis I (MPS I) and MPS VII are due to loss-of-function mutations within the genes that encode the lysosomal enzymes α-L-iduronidase and β-glucuronidase, respectively, and result in accumulation of glycosaminoglycans and multisystemic disease. Both disorders are associated with elast...
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Autors principals: | , , , , , , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
2009
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2838970/ https://ncbi.nlm.nih.gov/pubmed/20044292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2009.12.003 |
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