Pathogenesis of Mitral Valve Disease in Mucopolysaccharidosis VII Dogs

Mucopolysaccharidosis VII (MPS VII) is due to deficient activity of β-glucuronidase (GUSB) and results in the accumulation of glycosaminoglycans (GAGs) in lysosomes and multisystemic disease with cardiavascular manifestations. The goal here was to determine the pathogenesis of mitral valve (MV) dise...

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Detalhes bibliográficos
Main Authors: Bigg, Paul W., Baldo, Guilherme, Sleeper, Meg M., O'Donnell, Patricia A., Bai, Hanqing, Rokkam, Venkata R.P., Liu, Yuli, Wu, Susan, Giugliani, Roberto, Casal, Margret L., Haskins, Mark E., Ponder, Katherine P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800211/
https://ncbi.nlm.nih.gov/pubmed/23856419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2013.06.013
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