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2,6-Dithiopurine blocks toxicity and mutagenesis in human skin cells exposed to sulfur mustard analogs, 2-chloroethyl ethyl sulfide and 2-chloroethyl methyl sulfide
Sulfur mustard (bis-(2-chloroethyl)sulfide) is a well known chemical warfare agent that induces debilitating cutaneous toxicity in exposed individuals. It is also known to be carcinogenic and mutagenic due to its ability to damage DNA via electrophilic attack. We previously showed that a nucleophili...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2838951/ https://ncbi.nlm.nih.gov/pubmed/20050631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx9001918 |
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