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A persistent virus vector confers superior anti-tumor immunity, compared with a non-persistent vector

Active vaccination strategies using viral vectors often give disappointing protection from tumor development, and usually requires multiple immunizations. These approaches normally use viruses that cause acute infections, as they provoke potent CD8 T cell responses. Persistent virus vectors have not...

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Bibliografiske detaljer
Main Authors: Zhang, Weijun, Zhang, Tong, Turk, Mary-Jo, Usherwood, Edward J.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838928/
https://ncbi.nlm.nih.gov/pubmed/19921188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-009-0790-8
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