Neuroprotective effects of bis(7)-tacrine against glutamate-induced retinal ganglion cells damage

BACKGROUND: Glutamate-mediated excitotoxicity, primarily through N-methyl-D-aspartate (NMDA) receptors, may be an important cause of retinal ganglion cells (RGCs) death in glaucoma and several other retinal diseases. Bis(7)-tacrine is a noncompetitive NMDA receptors antagonist that can prevent gluta...

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Hauptverfasser: Fang, Jia Hua, Wang, Xing Hua, Xu, Zhi Rong, Jiang, Fa Gang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Research article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838896/
https://ncbi.nlm.nih.gov/pubmed/20199668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-11-31
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