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Neuroprotective effects of bis(7)-tacrine against glutamate-induced retinal ganglion cells damage
BACKGROUND: Glutamate-mediated excitotoxicity, primarily through N-methyl-D-aspartate (NMDA) receptors, may be an important cause of retinal ganglion cells (RGCs) death in glaucoma and several other retinal diseases. Bis(7)-tacrine is a noncompetitive NMDA receptors antagonist that can prevent gluta...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2838896/ https://ncbi.nlm.nih.gov/pubmed/20199668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-11-31 |
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