A at Single Nucleotide Polymorphism-358 Is Required for G at -420 to Confer the Highest Plasma Resistin in the General Japanese Population

Insulin resistance is a feature of type 2 diabetes. Resistin, secreted from adipocytes, causes insulin resistance in mice. We previously reported that the G/G genotype of single nucleotide polymorphism (SNP) at −420 (rs1862513) in the human resistin gene (RETN) increased susceptibility to type 2 dia...

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Detalhes bibliográficos
Main Authors: Onuma, Hiroshi, Tabara, Yasuharu, Kawamura, Ryoichi, Tanaka, Takashi, Ohashi, Jun, Nishida, Wataru, Takata, Yasunori, Ochi, Masaaki, Yamada, Kazuya, Kawamoto, Ryuichi, Kohara, Katsuhiko, Miki, Tetsuro, Makino, Hideichi, Osawa, Haruhiko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838794/
https://ncbi.nlm.nih.gov/pubmed/20300528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009718
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