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Role of protein tyrosine phosphatase SHP2 in barrier function of pulmonary endothelium

Pulmonary edema is mediated in part by disruption of interendothelial cell contacts. Protein tyrosine phosphatases (PTP) have been shown to affect both cell-extracellular matrix and cell-cell junctions. The SH2 domain-containing nonreceptor PTP, SHP2, is involved in intercellular signaling through d...

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Bibliographic Details
Main Authors: Grinnell, K. L., Casserly, B., Harrington, E. O.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838678/
https://ncbi.nlm.nih.gov/pubmed/20023173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00374.2009
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