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Signaling responses after exposure to 5α-dihydrotestosterone or 17β-estradiol in norepinephrine-induced hypertrophy of neonatal rat ventricular myocytes

Androgens appear to enhance, whereas estrogens mitigate, cardiac hypertrophy. However, signaling pathways in cells for short (3 min) and longer term (48 h) treatment with 17β-estradiol (E2) or 5α-dihydrotestosterone (DHT) are understudied. We compared the effect of adrenergic stimulation by norepine...

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Autors principals: Koshman, Yevgeniya E., Piano, Mariann R., Russell, Brenda, Schwertz, Dorie W.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838630/
https://ncbi.nlm.nih.gov/pubmed/20044473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00994.2009
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