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Tumor protein D52 expression and Ca(2+)-dependent phosphorylation modulates lysosomal membrane protein trafficking to the plasma membrane

Tumor protein D52 (also known as CRHSP-28) is highly expressed in multiple cancers and tumor-derived cell lines; however, it is normally abundant in secretory epithelia throughout the digestive system, where it has been implicated in Ca(2+)-dependent digestive enzyme secretion (41). Here we demonstr...

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Detalhes bibliográficos
Main Authors: Thomas, Diana D. H., Martin, Christina L., Weng, Ning, Byrne, Jennifer A., Groblewski, Guy E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838566/
https://ncbi.nlm.nih.gov/pubmed/20032513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00455.2009
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