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In vitro processing and secretion of mutant insulin proteins that cause permanent neonatal diabetes
Permanent neonatal diabetes mellitus is a rare form of insulin-requiring diabetes presenting within the first few weeks or months of life. Mutations in the insulin gene are the second most common cause of this form of diabetes. These mutations are located in critical regions of preproinsulin and are...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2838531/ https://ncbi.nlm.nih.gov/pubmed/19952343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00592.2009 |
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