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Penta-galloyl-glucose induces autophagy and caspase-independent programmed deaths in human PC-3 and mouse TRAMP-C2 prostate cancer cells

Penta-O-galloyl-β-D-glucose (PGG) suppresses the in vivo growth of human DU145 and PC-3 prostate cancer (PCa) xenografts in nude mice, suggesting potential utility as a PCa chemotherapeutic or chemopreventive agent. Our earlier work implicates caspase-mediated apoptosis in DU145 and LNCaP PCa cells...

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Detalhes bibliográficos
Main Authors: Hu, Hongbo, Chai, Yubo, Wang, Lei, Zhang, Jinhui, Lee, Hyo Jeong, Kim, Sung-Hoon, Lü, Junxuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838500/
https://ncbi.nlm.nih.gov/pubmed/19825802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0288
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