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Protection Against Chronic Pancreatitis and Pancreatic Fibrosis in Mice Over-Expressing Pancreatic Secretory Trypsin Inhibitor

OBJECTIVES: Mutations in the gene encoding for pancreatic secretory trypsin inhibitor (PSTI) can contribute to chronic pancreatitis. In the current study, we tested whether over-expression of pancreatic secretory trypsin inhibitor-I in mice protects against chronic pancreatitis and pancreatic fibros...

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Detalhes bibliográficos
Main Authors: Nathan, Jaimie D., Romac, Joelle, Peng, Ruth Y., Peyton, Michael, Rockey, Don C., Liddle, Rodger A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838384/
https://ncbi.nlm.nih.gov/pubmed/19904222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0b013e3181bc45e9
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