Mezlocillin Pharmacokinetics After Single Intravenous Doses to Patients with Varying Degrees of Renal Function

The pharmacokinetics of mezlocillin were examined after single 2- and 4-g intravenous injections to three groups of male patients with creatinine clearances of I ≥ 60, II = 21 to 59, and III ≤ 20 ml min(−1) 1.73 m(−2). The decline in serum antibiotic levels was biphasic in all groups, and serum data...

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Главные авторы: Frimodt-Möller, Niels, Maigaard, Sven, Toothaker, Roger D., Bundtzen, Robert W., Brodey, Mitchell V., Craig, William A., Welling, Peter G., Madsen, Paul O.
Формат: Artigo
Язык:Inglês
Опубликовано: 1980
Предметы:
Pharmacology and Therapeutics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC283838/
https://ncbi.nlm.nih.gov/pubmed/6446877
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