Smad3 Prevents β-Catenin Degradation and Facilitates β-Catenin Nuclear Translocation in Chondrocytes

Our previous study demonstrated that transforming growth factor (TGF)-β activates β-catenin signaling through Smad3 interaction with β-catenin in chondrocytes. In the present studies, we further investigated the detailed molecular mechanism of the cross-talk between TGF-β/Smad3 and Wnt/β-catenin sig...

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Main Authors: Zhang, Ming, Wang, Meina, Tan, Xiaohong, Li, Tian-Fang, Zhang, Ying E., Chen, Di
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Protein Synthesis and Degradation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838293/
https://ncbi.nlm.nih.gov/pubmed/20097766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.093526
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