A new polycythaemia vera-associated SOCS3 SH2 mutant (SOCS3(F136L)) cannot regulate erythropoietin responses

Recently several different JAK2 exon12 mutations have been identified in V617F negative polycythaemia vera (PV) or idiopathic erythrocytosis (IE) patients. The patients present with erythrocytosis, ligand-independent cell growth and low serum erythropoietin (EPO) levels. Within this group, a deletio...

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Detalhes bibliográficos
Main Authors: Suessmuth, Yvonne, Elliott, Joanne, Percy, Melanie J., Inami, Mitsuharu, Attal, Hila, Harrison, Claire N., Inokuchi, Koiti, McMullin, Mary-Frances, Johnston, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838228/
https://ncbi.nlm.nih.gov/pubmed/19735488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2009.07860.x
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