Gastrointestinal Delivery of Baculovirus Displaying Influenza Virus Hemagglutinin Protects Mice against Heterologous H5N1 Infection

The recent outbreaks of influenza A H5N1 virus in birds and humans have necessitated the development of potent H5N1 vaccines. In this study, we evaluated the protective potential of an immediate-early promoter-based baculovirus displaying hemagglutinin (BacHA) against highly pathogenic avian influen...

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Hlavní autoři: Prabakaran, Mookkan, Madhan, Selvaraj, Prabhu, Nayana, Qiang, Jia, Kwang, Jimmy
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838147/
https://ncbi.nlm.nih.gov/pubmed/20071572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02175-09
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