Rapid Escape from Preserved Cross-Reactive Neutralizing Humoral Immunity without Loss of Viral Fitness in HIV-1-Infected Progressors and Long-Term Nonprogressors

A substantial proportion of human immunodeficiency virus type 1 (HIV-1)-infected individuals has cross-reactive neutralizing activity in serum, with a similar prevalence in progressors and long-term nonprogressors (LTNP). We studied whether disease progression in the face of cross-reactive neutraliz...

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Main Authors: van Gils, Marit J., Bunnik, Evelien M., Burger, Judith A., Jacob, Yodit, Schweighardt, Becky, Wrin, Terri, Schuitemaker, Hanneke
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838121/
https://ncbi.nlm.nih.gov/pubmed/20071586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02622-09
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