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Acquisition of Complement Resistance through Incorporation of CD55/Decay-Accelerating Factor into Viral Particles Bearing Baculovirus GP64

A major obstacle to gene transduction by viral vectors is inactivation by human complement in vivo. One way to overcome this is to incorporate complement regulatory proteins, such as CD55/decay accelerating factor (DAF), into viral particles. Lentivirus vectors pseudotyped with the baculovirus envel...

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Bibliographische Detailangaben
Hauptverfasser: Kaname, Yuuki, Tani, Hideki, Kataoka, Chikako, Shiokawa, Mai, Taguwa, Shuhei, Abe, Takayuki, Moriishi, Kohji, Kinoshita, Taroh, Matsuura, Yoshiharu
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838113/
https://ncbi.nlm.nih.gov/pubmed/20071581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02519-09
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