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Baculovirus Induces Type I Interferon Production through Toll-Like Receptor-Dependent and -Independent Pathways in a Cell-Type-Specific Manner

Autographa californica nuclear polyhedrosis virus (AcNPV) is a double-stranded-DNA virus that is pathogenic to insects. AcNPV was shown to induce an innate immune response in mammalian immune cells and to confer protection of mice from lethal viral infection. In this study, we have shown that produc...

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Bibliographische Detailangaben
Hauptverfasser: Abe, Takayuki, Kaname, Yuuki, Wen, Xiaoyu, Tani, Hideki, Moriishi, Kohji, Uematsu, Satoshi, Takeuchi, Osamu, Ishii, Ken J., Kawai, Taro, Akira, Shizuo, Matsuura, Yoshiharu
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708616/
https://ncbi.nlm.nih.gov/pubmed/19474102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00679-09
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