Sulfotyrosines of the Kaposi's Sarcoma-Associated Herpesvirus G Protein-Coupled Receptor Promote Tumorigenesis through Autocrine Activation

The Kaposi's sarcoma-associated herpesvirus (KSHV) G protein-coupled receptor (vGPCR) is a bona fide signaling molecule that is implicated in KSHV-associated malignancies. Whereas vGPCR activates specific cellular signaling pathways in a chemokine-independent fashion, vGPCR binds a broad spectr...

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Bibliografiske detaljer
Main Authors: Feng, Hao, Sun, Zhifeng, Farzan, Michael R., Feng, Pinghui
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Transformation and Oncogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838108/
https://ncbi.nlm.nih.gov/pubmed/20106924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01939-09
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