Kaposi's Sarcoma-Associated Herpesvirus G-Protein-Coupled Receptor Prevents AU-Rich-Element-Mediated mRNA Decay

During lytic Kaposi's sarcoma-associated herpesvirus (KSHV) infection, host gene expression is severely restricted by a process of global mRNA degradation known as host shutoff, which rededicates translational machinery to the expression of viral proteins. A subset of host mRNAs is spared from...

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Detalhes bibliográficos
Main Authors: Corcoran, Jennifer A., Khaperskyy, Denys A., Johnston, Benjamin P., King, Christine A., Cyr, David P., Olsthoorn, Alisha V., McCormick, Craig
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Transformation and Oncogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421767/
https://ncbi.nlm.nih.gov/pubmed/22696654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00597-12
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