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Functional Analysis of the RdxA and RdxB Nitroreductases of Campylobacter jejuni Reveals that Mutations in rdxA Confer Metronidazole Resistance

Campylobacter jejuni is a leading cause of gastroenteritis in humans and a commensal bacterium of the intestinal tracts of many wild and agriculturally significant animals. We identified and characterized a locus, which we annotated as rdxAB, encoding two nitroreductases. RdxA was found to be respon...

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Detalhes bibliográficos
Main Authors: Ribardo, Deborah A., Bingham-Ramos, Lacey K., Hendrixson, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838047/
https://ncbi.nlm.nih.gov/pubmed/20118248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01638-09
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