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Comparative Transcriptome Analysis Reveals Novel Roles of the Ras and Cyclic AMP Signaling Pathways in Environmental Stress Response and Antifungal Drug Sensitivity in Cryptococcus neoformans

The cyclic AMP (cAMP) pathway plays a central role in the growth, differentiation, and virulence of pathogenic fungi, including Cryptococcus neoformans. Three upstream signaling regulators of adenylyl cyclase (Cac1), Ras, Aca1, and Gpa1, have been demonstrated to control the cAMP pathway in C. neofo...

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Main Authors: Maeng, Shinae, Ko, Young-Joon, Kim, Gyu-Bum, Jung, Kwang-Woo, Floyd, Anna, Heitman, Joseph, Bahn, Yong-Sun
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837985/
https://ncbi.nlm.nih.gov/pubmed/20097740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00309-09
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