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Comparative Transcriptome Analysis Reveals Novel Roles of the Ras and Cyclic AMP Signaling Pathways in Environmental Stress Response and Antifungal Drug Sensitivity in Cryptococcus neoformans

The cyclic AMP (cAMP) pathway plays a central role in the growth, differentiation, and virulence of pathogenic fungi, including Cryptococcus neoformans. Three upstream signaling regulators of adenylyl cyclase (Cac1), Ras, Aca1, and Gpa1, have been demonstrated to control the cAMP pathway in C. neofo...

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Bibliografski detalji
Glavni autori: Maeng, Shinae, Ko, Young-Joon, Kim, Gyu-Bum, Jung, Kwang-Woo, Floyd, Anna, Heitman, Joseph, Bahn, Yong-Sun
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837985/
https://ncbi.nlm.nih.gov/pubmed/20097740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00309-09
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