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Comparative Transcriptome Analysis Reveals Novel Roles of the Ras and Cyclic AMP Signaling Pathways in Environmental Stress Response and Antifungal Drug Sensitivity in Cryptococcus neoformans

The cyclic AMP (cAMP) pathway plays a central role in the growth, differentiation, and virulence of pathogenic fungi, including Cryptococcus neoformans. Three upstream signaling regulators of adenylyl cyclase (Cac1), Ras, Aca1, and Gpa1, have been demonstrated to control the cAMP pathway in C. neofo...

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Autors principals: Maeng, Shinae, Ko, Young-Joon, Kim, Gyu-Bum, Jung, Kwang-Woo, Floyd, Anna, Heitman, Joseph, Bahn, Yong-Sun
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837985/
https://ncbi.nlm.nih.gov/pubmed/20097740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00309-09
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