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Intrarenal distribution of trimethoprim and sulfamethoxazole.

In the present study, rats were given trimethoprim (TMP, 10 mg/kg), sulfamethoxazole (SMZ, 50 mg/kg), or a combination of the respective doses of TMP and SMZ. Thirty-six rats received each of the drugs studied. Six recipients of a compound (or mixture) were evaluated hourly, from 1 to 6 h after intr...

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Bibliographic Details
Main Authors: Trottier, S, Bergeron, M G, Lessard, C
Format: Artigo
Language:Inglês
Published: 1980
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC283795/
https://ncbi.nlm.nih.gov/pubmed/7425603
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