Failure of trimethoprim-sulfamethoxazole therapy in experimental enterococcal endocarditis.

To assess the potential efficacy of trimethoprim-sulfamethoxazole (TMP-SMX) against serious enterococcal infections, we used a rat enterococcal endocarditis model comparing TMP-SMX therapy (500 mg of TMP plus 2,500 mg of SMX per kg of body weight per day given every 8 h by intragastric gavage) with...

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Autores principales: Grayson, M L, Thauvin-Eliopoulos, C, Eliopoulos, G M, Yao, J D, DeAngelis, D V, Walton, L, Woolley, J L, Moellering, R C
Formato: Artigo
Lenguaje:Inglês
Publicado: 1990
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC171927/
https://ncbi.nlm.nih.gov/pubmed/2126691
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