Failure of trimethoprim-sulfamethoxazole therapy in experimental enterococcal endocarditis.

To assess the potential efficacy of trimethoprim-sulfamethoxazole (TMP-SMX) against serious enterococcal infections, we used a rat enterococcal endocarditis model comparing TMP-SMX therapy (500 mg of TMP plus 2,500 mg of SMX per kg of body weight per day given every 8 h by intragastric gavage) with...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Grayson, M L, Thauvin-Eliopoulos, C, Eliopoulos, G M, Yao, J D, DeAngelis, D V, Walton, L, Woolley, J L, Moellering, R C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171927/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2126691/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.9.1792
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