Validation of Candidate Causal Genes for Abdominal Obesity Which Affect Shared Metabolic Pathways and Networks

A major task in dissecting the genetics of complex traits is to identify causal genes for disease phenotypes. We previously developed a method to infer causal relationships among genes through the integration of DNA variation, gene transcription, and phenotypic information. Here we validated our met...

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Autores principales: Yang, Xia, Deignan, Joshua L., Qi, Hongxiu, Zhu, Jun, Qian, Su, Zhong, Judy, Torosyan, Gevork, Majid, Sana, Falkard, Brie, Kleinhanz, Robert R., Karlsson, Jenny, Castellani, Lawrence W., Mumick, Sheena, Wang, Kai, Xie, Tao, Coon, Michael, Zhang, Chunsheng, Estrada-Smith, Daria, Farber, Charles R., Wang, Susanna S., Van Nas, Atila, Ghazalpour, Anatole, Zhang, Bin, MacNeil, Douglas J., Lamb, John R., Dipple, Katrina M., Reitman, Marc L., Mehrabian, Margarete, Lum, Pek Y., Schadt, Eric E., Lusis, Aldons J., Drake, Thomas A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837947/
https://ncbi.nlm.nih.gov/pubmed/19270708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.325
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