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Transcriptional regulation of the AP-1 and Nrf2 target gene sulfiredoxin

“Two-cysteine” peroxiredoxins are antioxidant enzymes that exert a cytoprotective effect in many models of oxidative stress. However, under highly oxidizing conditions they can be inactivated through hyperoxidation of their peroxidatic active site cysteine residue. Sulfiredoxin can reverse this hype...

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Autors principals: Soriano, Francesc X., Baxter, Paul, Murray, Lyndsay M., Sporn, Michael B., Gillingwater, Thomas H., Hardingham, Giles E.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837916/
https://ncbi.nlm.nih.gov/pubmed/19326073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-009-0050-y
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