ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function

This review focuses on the emerging evidence that reactive oxygen species (ROS) derived from glucose metabolism, such as H(2)O(2), act as metabolic signaling molecules for glucose-stimulated insulin secretion (GSIS) in pancreatic beta-cells. Particular emphasis is placed on the potential inhibitory...

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Autores principales: Pi, Jingbo, Zhang, Qiang, Fu, Jingqi, Woods, Courtney G., Hou, Yongyong, Corkey, Barbara E, Collins, Sheila, Andersen, Melvin E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837798/
https://ncbi.nlm.nih.gov/pubmed/19501608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2009.05.025
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