Cardiac Arrhythmias Induced by Glutathione Oxidation can be Inhibited by Preventing Mitochondrial Depolarization

We have previously proposed that the heterogeneous collapse of mitochondrial inner membrane potential (ΔΨ(m)) during ischemia and reperfusion contributes to arrhythmogenesis through the formation of metabolic sinks in the myocardium, wherein clusters of myocytes with uncoupled mitochondria and high...

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Hauptverfasser: Brown, David A., Aon, Miguel A., Frasier, Chad R., Sloan, Ruben C., Maloney, Andrew H., Anderson, Ethan J., O'Rourke, Brian
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837795/
https://ncbi.nlm.nih.gov/pubmed/19962380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.11.011
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