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Immunity of replicating Mu to self-integration: a novel mechanism employing MuB protein

We describe a new immunity mechanism that protects actively replicating/transposing Mu from self-integration. We show that this mechanism is distinct from the established cis-immunity mechanism, which operates by removal of MuB protein from DNA adjacent to Mu ends. MuB normally promotes integration...

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Bibliografiske detaljer
Main Authors: Ge, Jun, Lou, Zheng, Harshey, Rasika M
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837660/
https://ncbi.nlm.nih.gov/pubmed/20226074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1759-8753-1-8
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