BMP-2 Modulates β-Catenin Signaling Through Stimulation of Lrp5 Expression and Inhibition of β-TrCP Expression in Osteoblasts

Canonical BMP and Wnt signaling pathways play critical roles in regulation of osteoblast function and bone formation. Recent studies demonstrate that BMP-2 acts synergistically with β-catenin to promote osteoblast differentiation. To determine the molecular mechanisms of the signaling cross-talk bet...

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Main Authors: Zhang, Ming, Yan, Ying, Lim, Yong-bin, Tang, Dezhi, Xie, Rong, Chen, Ann, Tai, Peter, Harris, Stephen E., Xing, Lianping, Qin, Yi-Xian, Chen, Di
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837602/
https://ncbi.nlm.nih.gov/pubmed/19795382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22319
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