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Pathogenicity in mice of strains of herpes simplex virus which are resistant to acyclovir in vitro and in vivo.

Mice infected with three different isolates of herpes simplex virus (HSV) and treated with acyclovir (acycloguanosine; ACV) showed low levels of virus replication during the acute phase of infection. However, virus isolated from such treated mice did not show increased resistance to ACV. In contrast...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Field, H J, Darby, G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283760/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6247969/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.17.2.209
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