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Pathogenicity in mice of strains of herpes simplex virus which are resistant to acyclovir in vitro and in vivo.

Mice infected with three different isolates of herpes simplex virus (HSV) and treated with acyclovir (acycloguanosine; ACV) showed low levels of virus replication during the acute phase of infection. However, virus isolated from such treated mice did not show increased resistance to ACV. In contrast...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Field, H J, Darby, G
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1980
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283760/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6247969/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.17.2.209
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