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Stathmin/Op18 is a novel mediator of vinblastine activity

Microtubule dynamic instability is tightly regulated by stabilizing and destabilizing proteins, the latter being exemplified by stathmin/Op18, a protein known to destabilize microtubules. Studies in cells have indicated that the level of stathmin expression modifies the cytotoxicity of antimicrotubu...

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Detalhes bibliográficos
Main Authors: Devred, Francois, Tsvetkov, Philipp O., Barbier, Pascale, Allegro, Diane, Horwitz, Susan Band, Makarov, Alexander A., Peyrot, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837597/
https://ncbi.nlm.nih.gov/pubmed/18588888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2008.06.035
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