Stathmin and Interfacial Microtubule Inhibitors Recognize a Naturally Curved Conformation of Tubulin Dimers

Tubulin is able to switch between a straight microtubule-like structure and a curved structure in complex with the stathmin-like domain of the RB3 protein (T(2)RB3). GTP hydrolysis following microtubule assembly induces protofilament curvature and disassembly. The conformation of the labile tubulin...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Barbier, Pascale, Dorléans, Audrey, Devred, Francois, Sanz, Laura, Allegro, Diane, Alfonso, Carlos, Knossow, Marcel, Peyrot, Vincent, Andreu, Jose M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
Matèries:
Protein Structure and Folding
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951239/
https://ncbi.nlm.nih.gov/pubmed/20675373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.141929
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars