Comparative Pharmacokinetics of Ceforanide (BL-S786R) and Cefazolin in Laboratory Animals and Humans

Ceforanide (BL-S786R) is a new, broad-spectrum, parenteral cephalosporin. Pharmacokinetic properties were determined in rats (100 mg/kg), rabbits (30 mg/kg), dogs (25 mg/kg), and humans (2 g or 30 mg/kg) and compared with equivalent single doses of cefazolin. Plasma half-lives for ceforanide and cef...

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Bibliografiske detaljer
Main Authors: Lee, Francis H., Pfeffer, Morris, Van Harken, Donald R., Smyth, Robert D., Hottendorf, Girard H.
Format: Artigo
Sprog:Inglês
Udgivet: 1980
Fag:
Pharmacology and Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC283756/
https://ncbi.nlm.nih.gov/pubmed/7387141
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