Comparative Pharmacokinetics of Ceforanide (BL-S786R) and Cefazolin in Laboratory Animals and Humans

Ceforanide (BL-S786R) is a new, broad-spectrum, parenteral cephalosporin. Pharmacokinetic properties were determined in rats (100 mg/kg), rabbits (30 mg/kg), dogs (25 mg/kg), and humans (2 g or 30 mg/kg) and compared with equivalent single doses of cefazolin. Plasma half-lives for ceforanide and cef...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Lee, Francis H., Pfeffer, Morris, Van Harken, Donald R., Smyth, Robert D., Hottendorf, Girard H.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1980
Fag:	Pharmacology and Therapeutics
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283756/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7387141/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.17.2.188
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