DOXORUBICIN RESISTANCE IN A NOVEL IN VITRO MODEL OF HUMAN PLEOMORPHIC LIPOSARCOMA ASSOCIATED WITH ALTERNATIVE LENGTHENING OF TELOMERES

Soft tissue sarcomas are a diverse set of fatal human tumors where few agents have demonstrable clinical efficacy, with the standard therapeutic combination of doxorubicin and ifosfamide showing only a 25–30% response rate in large multi-institutional trials. Although liposarcomas are the most commo...

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Hlavní autoři: Mitchell, Marcy A., Johnson, Jay E., Pascarelli, Kara, Beeharry, Neil, Chiourea, Maria, Gagos, Sarantis, Lev, Dina, von Mehren, Margaret, Kipling, David, Broccoli, Dominique
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837520/
https://ncbi.nlm.nih.gov/pubmed/20197395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0705
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