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Substrate Induced Population Shifts and Stochastic Gating in the PBCV-1 mRNA Capping Enzyme

[Image: see text] The 317 residue PBCV-1 mRNA capping enzyme catalyzes the second enzymatic reaction in the formation of an N-7-methyl-GMP cap on the 5′-end of the nascent mRNA. It is composed of two globular domains bound by a short flexible peptide linker, which have been shown to undergo opening...

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Detaylı Bibliyografya
Asıl Yazarlar: Swift, Robert V., McCammon, J. Andrew
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2009
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837470/
https://ncbi.nlm.nih.gov/pubmed/19301911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja808064g
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